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The Atg5–Atg12 conjugate associates with innate antiviral immune responses

Autophagy is an essential process for physiological homeostasis, but its role in viral infection is only beginning to be elucidated. We show here that the Atg5–Atg12 conjugate, a key regulator of the autophagic process, plays an important role in innate antiviral immune responses. Atg5-deficient mou...

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Détails bibliographiques
Auteurs principaux: Jounai, Nao, Takeshita, Fumihiko, Kobiyama, Kouji, Sawano, Asako, Miyawaki, Atsushi, Xin, Ke-Qin, Ishii, Ken J., Kawai, Taro, Akira, Shizuo, Suzuki, Koichi, Okuda, Kenji
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955809/
https://ncbi.nlm.nih.gov/pubmed/17709747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704014104
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