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Human Immunodeficiency Virus Type 1 gp120 Induces Apoptosis in Human Primary Neurons through Redox-Regulated Activation of Neutral Sphingomyelinase
Human immunodeficiency virus type 1 (HIV-1) infection is known to cause disorders of the CNS, including HIV-associated dementia (HAD). HIV-1 coat protein gp120 (glycoprotein 120) induces neuronal apoptosis and has been implicated in the pathogenesis of HAD. However, the mechanism by which gp120 caus...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955476/ https://ncbi.nlm.nih.gov/pubmed/15509740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3085-04.2004 |
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