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Lsh controls Hox gene silencing during development

Polycomb-mediated repression and DNA methylation are important epigenetic mechanisms of gene silencing. Recent evidence suggests a functional link between the polycomb repressive complex (PRC) and Dnmts in cancer cells. Here we provide evidence that Lsh, a regulator of DNA methylation, is also invol...

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Autors principals: Xi, Sichuan, Zhu, Heming, Xu, Hong, Schmidtmann, Anja, Geiman, Theresa M., Muegge, Kathrin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955459/
https://ncbi.nlm.nih.gov/pubmed/17726103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703669104
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