Genetic variations of Toll‐like receptor 9 predispose to systemic lupus erythematosus in Japanese population

BACKGROUND: Systemic lupus erythematosus (SLE) is characterised by dysregulation of autoreactive lymphocytes and antigen‐presenting cells. Signalling through Toll‐like receptor 9 (TLR9), a mediator of innate immune responses, has a role in activation of dendritic cells and autoreactive B cells. OBJE...

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Autors principals: Tao, Kayoko, Fujii, Mutsuko, Tsukumo, Shin‐ichi, Maekawa, Yoichi, Kishihara, Kenji, Kimoto, Yasutaka, Horiuchi, Takahiko, Hisaeda, Hajime, Akira, Shizuo, Kagami, Shoji, Yasutomo, Koji
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2007
Matèries:
Extended Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955115/
https://ncbi.nlm.nih.gov/pubmed/17344245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.065961
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