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Genetic variations of Toll‐like receptor 9 predispose to systemic lupus erythematosus in Japanese population
BACKGROUND: Systemic lupus erythematosus (SLE) is characterised by dysregulation of autoreactive lymphocytes and antigen‐presenting cells. Signalling through Toll‐like receptor 9 (TLR9), a mediator of innate immune responses, has a role in activation of dendritic cells and autoreactive B cells. OBJE...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955115/ https://ncbi.nlm.nih.gov/pubmed/17344245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.065961 |
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