Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells

BACKGROUND: Tissue plasminogen activator (tPA) is the major activator of plasminogen in plasma. This serine protease is overexpressed by exocrine pancreas tumour cells, where it promotes tumour cell proliferation, growth, and invasion. Here we have explored the signalling pathways used by tPA to act...

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Bibliografiska uppgifter
Huvudupphovsmän: Hurtado, Mariano, Lozano, Juan José, Castellanos, Elisabeth, López‐Fernández, Luis A, Harshman, Keith, Martínez‐A, Carlos, Ortiz, Angel R, Thomson, Timothy M, Paciucci, Rosanna
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMJ Group 2007
Ämnen:
Pancreatic Cancer
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954978/
https://ncbi.nlm.nih.gov/pubmed/17452424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.097188
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