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Safety and efficacy of leflunomide in primary Sjögren's syndrome: a phase II pilot study

BACKGROUND: For invalidating symptoms in primary Sjögren's syndrome (pSS), there is still a need for easy‐to‐administer, cost‐effective and well‐tolerated systemic treatment. Leflunomide (LEF) is structurally unrelated to other immunomodulatory drugs and might be efficacious in pSS, given its c...

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Detalhes bibliográficos
Main Authors: van Woerkom, J M, Kruize, A A, Geenen, R, van Roon, E N, Goldschmeding, R, Verstappen, S M M, van Roon, J A G, Bijlsma, J W J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954693/
https://ncbi.nlm.nih.gov/pubmed/17223657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.060905
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