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The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I

Bacteriophage T7 DNA polymerase shares extensive sequence homology with Escherichia coli DNA polymerase I. However, in vivo, E. coli DNA polymerase I is involved primarily in the repair of DNA whereas T7 DNA polymerase is responsible for the replication of the viral genome. In accord with these role...

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Hlavní autoři: Bedford, Ella, Tabor, Stanley, Richardson, Charles C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19538/
https://ncbi.nlm.nih.gov/pubmed/9012809
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