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The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I

Bacteriophage T7 DNA polymerase shares extensive sequence homology with Escherichia coli DNA polymerase I. However, in vivo, E. coli DNA polymerase I is involved primarily in the repair of DNA whereas T7 DNA polymerase is responsible for the replication of the viral genome. In accord with these role...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Bedford, Ella, Tabor, Stanley, Richardson, Charles C.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1997
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012809/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.479
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