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Tests of the Extension and Deadbolt Models of Integrin Activation
Despite extensive evidence that integrin conformational changes between bent and extended conformations regulate affinity for ligands, an alternative hypothesis has been proposed in which a “deadbolt” can regulate affinity for ligand in the absence of extension. Here, we tested both the deadbolt and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952534/ https://ncbi.nlm.nih.gov/pubmed/17301049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700249200 |
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