Conferring RNA polymerase Activity to a DNA polymerase: A single residue in reverse transcriptase controls substrate selection

The traditional classification of nucleic acid polymerases as either DNA or RNA polymerases is based, in large part, on their fundamental preference for the incorporation of either deoxyribonucleotides or ribonucleotides during chain elongation. The refined structure determination of Moloney murine...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Gao, Guangxia, Orlova, Marianna, Georgiadis, Millie M., Hendrickson, Wayne A., Goff, Stephen P.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.407
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