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Crystallization of a 2:2 complex of granulocyte-colony stimulating factor (GCSF) with the ligand-binding region of the GCSF receptor

The granulocyte-colony stimulating factor (GCSF) receptor receives signals for regulating the maturation, proliferation and differentiation of the precursor cells of neutrophilic granulocytes. The signalling complex composed of two GCSFs (GCSF, 19 kDa) and two GCSF receptors (GCSFR, 34 kDa) consisti...

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Detalhes bibliográficos
Main Authors: Honjo, Eijiro, Tamada, Taro, Maeda, Yoshitake, Koshiba, Takumi, Matsukura, Yasuko, Okamoto, Tomoyuki, Ishibashi, Matsujiro, Tokunaga, Masao, Kuroki, Ryota
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952362/
https://ncbi.nlm.nih.gov/pubmed/16511159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105023080
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