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Initiating a crystallographic analysis of recombinant (S)-2-hydroxypropylphosphonic acid epoxidase from Streptomyces wedmorensis

The oxirane (1R,2S)-1,2-epoxypropylphosphonic acid (fosfomycin) is a natural product antibiotic produced in Streptomyces wedmorensis by the metal-ion-dependent (S)-2-hydroxypropylphosphonic acid epoxidase. This epoxidase is highly unusual since it has no requirement for a haem prosthetic group. The...

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Autores principales: Cameron, Scott, McLuskey, Karen, Chamberlayne, Rachel, Hallyburton, Irene, Hunter, William N.
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952317/
https://ncbi.nlm.nih.gov/pubmed/16511089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105012376
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