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MdaB from Escherichia coli: cloning, purification, crystallization and preliminary X-ray analysis

The gene mdaB from Escherichia coli encodes an enzyme with activity similar to that of mammalian DT-diaphorase. It has been reported that the protein is able to confer resistance to the antibiotics DMP 840, adriamycin and etoposide. The gene was cloned and overexpressed in E. coli, allowing purifica...

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Main Authors: Adams, Melanie A., Iannuzzi, Pietro, Jia, Zongchao
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952255/
https://ncbi.nlm.nih.gov/pubmed/16511004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105001545
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