Llwytho...
Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking
BACKGROUND: Pathological accumulation of cholesterol in late endosomes is observed in lysosomal storage diseases such as Niemann-Pick type C. We here analyzed the effects of cholesterol accumulation in NPC cells, or as phenocopied by the drug U18666A, on late endosomes membrane organization and dyna...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Public Library of Science
2007
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952175/ https://ncbi.nlm.nih.gov/pubmed/17786222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000851 |
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