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Linear Distance from the Locus Control Region Determines ɛ-Globin Transcriptional Activity

Enhancer elements modulate promoter activity over vast chromosomal distances, and mechanisms that ensure restrictive interactions between promoters and enhancers are critical for proper control of gene expression. The human β-globin locus control region (LCR) activates expression of five genes in er...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shimotsuma, Motoshi, Matsuzaki, Hitomi, Tanabe, Osamu, Campbell, Andrew D., Engel, James Douglas, Fukamizu, Akiyoshi, Tanimoto, Keiji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952132/
https://ncbi.nlm.nih.gov/pubmed/17548470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00602-07
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