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Enhanced Sensitivity to Cholera Toxin in ADP-Ribosylarginine Hydrolase-Deficient Mice

Cholera toxin (CT) produced by Vibrio cholerae causes the devastating diarrhea of cholera by catalyzing the ADP-ribosylation of the α subunit of the intestinal G(s) protein (G(sα)), leading to characteristic water and electrolyte losses. Mammalian cells contain ADP-ribosyltransferases similar to CT...

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Detalles Bibliográficos
Main Authors: Kato, Jiro, Zhu, Jianfeng, Liu, Chengyu, Moss, Joel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952103/
https://ncbi.nlm.nih.gov/pubmed/17526733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00302-07
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