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Prolonged Sox4 Expression in Oligodendrocytes Interferes with Normal Myelination in the Central Nervous System

The highly related transcription factors Sox4 and Sox11 are both expressed in oligodendrocyte precursors. Yet whether they have a function in oligodendrocyte development is unknown. By overexpressing Sox4 under the control of 3.1 kb of 5′ flanking sequences of the myelin basic protein gene in transg...

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Detalhes bibliográficos
Main Authors: Potzner, Michaela R., Griffel, Carola, Lütjen-Drecoll, Elke, Bösl, Michael R., Wegner, Michael, Sock, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952099/
https://ncbi.nlm.nih.gov/pubmed/17515609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00339-07
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