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Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10

Sox10 is a high-mobility-group transcriptional regulator in early neural crest. Without Sox10, no glia develop throughout the peripheral nervous system. Here we show that Sox10 is restricted in the central nervous system to myelin-forming oligodendroglia. In Sox10-deficient mice progenitors develop,...

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Detalhes bibliográficos
Main Authors: Stolt, C. Claus, Rehberg, Stephan, Ader, Marius, Lommes, Petra, Riethmacher, Dieter, Schachner, Melitta, Bartsch, Udo, Wegner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155320/
https://ncbi.nlm.nih.gov/pubmed/11799060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.215802
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