Role of Primary Human Alveolar Epithelial Cells in Host Defense against Francisella tularensis Infection

Francisella tularensis, an intracellular pathogen, is highly virulent when inhaled. Alveolar epithelial type I (ATI) and type II (ATII) cells line the majority of the alveolar surface and respond to inhaled pathogenic bacteria via cytokine secretion. We hypothesized that these cells contribute to th...

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Détails bibliographiques
Auteurs principaux: Gentry, Megan, Taormina, Joanna, Pyles, Richard B., Yeager, Linsey, Kirtley, Michelle, Popov, Vsevolod L., Klimpel, Gary, Eaves-Pyles, Tonyia
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Host Response and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951971/
https://ncbi.nlm.nih.gov/pubmed/17502386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00157-07
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