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Toll-Like Receptor 3 Agonist Protection against Experimental Francisella tularensis Respiratory Tract Infection
We investigated whether Toll-like receptor 3 (TLR3) stimulation would protect the host from inhaled Francisella tularensis. TLR3 is expressed by respiratory epithelial cells and macrophages and can be activated by a synthetic double-stranded RNA ligand called polyinosine-polycytosine [poly(I:C)]. Th...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849393/ https://ncbi.nlm.nih.gov/pubmed/20123717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00736-09 |
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