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Phosphorylated AbsA2 Negatively Regulates Antibiotic Production in Streptomyces coelicolor through Interactions with Pathway-Specific Regulatory Gene Promoters

The AbsA two-component signal transduction system, comprised of the sensor kinase AbsA1 and the response regulator AbsA2, acts as a negative regulator of antibiotic production in Streptomyces coelicolor, for which the phosphorylated form of AbsA2 (AbsA2∼P) is the agent of repression. In this study,...

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Detalhes bibliográficos
Main Authors: McKenzie, Nancy L., Nodwell, Justin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951880/
https://ncbi.nlm.nih.gov/pubmed/17513473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00305-07
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