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Biochemical Activities of the absA Two-Component System of Streptomyces coelicolor

The AbsA1 sensor kinase and its cognate response regulator AbsA2 are important regulators of antibiotic synthesis in Streptomyces coelicolor. While certain point mutations in absA1 reduce or eliminate the synthesis of several antibiotics, null mutations in these genes bring about enhanced antibiotic...

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Bibliografiske detaljer
Main Authors: Sheeler, Nancy L., MacMillan, Susan V., Nodwell, Justin R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC543558/
https://ncbi.nlm.nih.gov/pubmed/15629939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.2.687-696.2005
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