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Mycobacterial Nonhomologous End Joining Mediates Mutagenic Repair of Chromosomal Double-Strand DNA Breaks

Bacterial nonhomologous end joining (NHEJ) is a recently described DNA repair pathway best characterized in mycobacteria. Bacterial NHEJ proteins LigD and Ku have been analyzed biochemically, and their roles in linear plasmid repair in vivo have been verified genetically; yet the contributions of NH...

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Detalhes bibliográficos
Main Authors: Stephanou, Nicolas C., Gao, Feng, Bongiorno, Paola, Ehrt, Sabine, Schnappinger, Dirk, Shuman, Stewart, Glickman, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951864/
https://ncbi.nlm.nih.gov/pubmed/17496093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00332-07
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