Identification of Regions Critically Affecting Kinetics and Allosteric Regulation of the Escherichia coli ADP-Glucose Pyrophosphorylase by Modeling and Pentapeptide-Scanning Mutagenesis

ADP-glucose pyrophosphorylase (ADP-Glc PPase) is the enzyme responsible for the regulation of bacterial glycogen synthesis. To perform a structure-function relationship study of the Escherichia coli ADP-Glc PPase enzyme, we studied the effects of pentapeptide insertions at different positions in the...

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Bibliografiska uppgifter
Huvudupphovsmän: Ballicora, Miguel A., Erben, Esteban D., Yazaki, Terutaka, Bertolo, Ana L., Demonte, Ana M., Schmidt, Jennifer R., Aleanzi, Mabel, Bejar, Clarisa M., Figueroa, Carlos M., Fusari, Corina M., Iglesias, Alberto A., Preiss, Jack
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Enzymes and Proteins
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951854/
https://ncbi.nlm.nih.gov/pubmed/17496097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00481-07
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