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Allosteric Control of Substrate Specificity of the Escherichia coli ADP-Glucose Pyrophosphorylase

The substrate specificity of enzymes is crucial to control the fate of metabolites to different pathways. However, there is growing evidence that many enzymes can catalyze alternative reactions. This promiscuous behavior has important implications in protein evolution and the acquisition of new func...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Ebrecht, Ana C., Solamen, Ligin, Hill, Benjamin L., Iglesias, Alberto A., Olsen, Kenneth W., Ballicora, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474683/
https://ncbi.nlm.nih.gov/pubmed/28674689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00041
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