Allosteric Control of Substrate Specificity of the Escherichia coli ADP-Glucose Pyrophosphorylase

The substrate specificity of enzymes is crucial to control the fate of metabolites to different pathways. However, there is growing evidence that many enzymes can catalyze alternative reactions. This promiscuous behavior has important implications in protein evolution and the acquisition of new func...

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Bibliographic Details
Published in:Front Chem
Main Authors: Ebrecht, Ana C., Solamen, Ligin, Hill, Benjamin L., Iglesias, Alberto A., Olsen, Kenneth W., Ballicora, Miguel A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474683/
https://ncbi.nlm.nih.gov/pubmed/28674689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00041
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