Potentiation of Astrogliogenesis by STAT3-Mediated Activation of Bone Morphogenetic Protein-Smad Signaling in Neural Stem Cells

Astrocytes play important roles in brain development and injury response. Transcription factors STAT3 and Smad1, activated by leukemia inhibitory factor (LIF) and bone morphogenetic protein 2 (BMP2), respectively, form a complex with the coactivator p300 to synergistically induce astrocytes from neu...

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Main Authors: Fukuda, Shinji, Abematsu, Masahiko, Mori, Hiroyuki, Yanagisawa, Makoto, Kagawa, Tetsushi, Nakashima, Kinichi, Yoshimura, Akihiko, Taga, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951480/
https://ncbi.nlm.nih.gov/pubmed/17452461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02435-06
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