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An Adenovirus Vector-Mediated Reverse Genetics System for Influenza A Virus Generation

Plasmid-based reverse genetics systems allow the generation of influenza A virus entirely from cloned cDNA. However, since the efficiency of virus generation is dependent on the plasmid transfection efficiency of cells, virus generation is difficult in cells approved for vaccine production that have...

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Bibliografiske detaljer
Main Authors: Ozawa, Makoto, Goto, Hideo, Horimoto, Taisuke, Kawaoka, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951417/
https://ncbi.nlm.nih.gov/pubmed/17596315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01042-07
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