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An Adenovirus Vector-Mediated Reverse Genetics System for Influenza A Virus Generation

Plasmid-based reverse genetics systems allow the generation of influenza A virus entirely from cloned cDNA. However, since the efficiency of virus generation is dependent on the plasmid transfection efficiency of cells, virus generation is difficult in cells approved for vaccine production that have...

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Detalhes bibliográficos
Main Authors: Ozawa, Makoto, Goto, Hideo, Horimoto, Taisuke, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951417/
https://ncbi.nlm.nih.gov/pubmed/17596315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01042-07
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