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Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus

Infection of eukaryotic cells by enveloped viruses requires the merging of viral and cellular membranes. Highly specific viral surface glycoproteins, named fusion proteins, catalyze this reaction by overcoming inherent energy barriers. Hepatitis C virus (HCV) is an enveloped virus that belongs to th...

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Bibliografiske detaljer
Main Authors: Lavillette, Dimitri, Pécheur, Eve-Isabelle, Donot, Peggy, Fresquet, Judith, Molle, Jennifer, Corbau, Romuald, Dreux, Marlène, Penin, François, Cosset, François-Loïc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951381/
https://ncbi.nlm.nih.gov/pubmed/17537855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02642-06
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