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Coreceptor Switch in R5-Tropic Simian/Human Immunodeficiency Virus-Infected Macaques

The basis for the switch from CCR5 to CXCR4 coreceptor usage seen in ∼50% of human immunodeficiency virus type 1 (HIV-1) subtype B-infected individuals as disease advances is not well understood. Among the reasons proposed are target cell limitation and better immune recognition of the CXCR4 (X4)-tr...

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Autores principales: Ho, Siu-hong, Tasca, Silvana, Shek, Lili, Li, Amy, Gettie, Agegnehu, Blanchard, James, Boden, Daniel, Cheng-Mayer, Cecilia
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951359/
https://ncbi.nlm.nih.gov/pubmed/17537860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00759-07
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