A Recombinant Human Monoclonal Antibody to Human Metapneumovirus Fusion Protein That Neutralizes Virus In Vitro and Is Effective Therapeutically In Vivo

Human metapneumovirus (hMPV) is a recently discovered paramyxovirus that is a major cause of lower-respiratory-tract disease. hMPV is associated with more severe disease in infants and persons with underlying medical conditions. Animal studies have shown that the hMPV fusion (F) protein alone is cap...

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Detalhes bibliográficos
Main Authors: Williams, John V., Chen, Zhifeng, Cseke, Gabriella, Wright, David W., Keefer, Christopher J., Tollefson, Sharon J., Hessell, Ann, Podsiad, Amy, Shepherd, Bryan E., Sanna, Pietro Paolo, Burton, Dennis R., Crowe, James E., Williamson, R. Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951312/
https://ncbi.nlm.nih.gov/pubmed/17522220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00106-07
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