Pneumolysin Causes Neuronal Cell Death through Mitochondrial Damage

Bacterial toxins such as pneumolysin are key mediators of cytotoxicity in infections. Pneumolysin is a pore-forming toxin released by Streptococcus pneumoniae, the major cause of bacterial meningitis. We found that pneumolysin is the pneumococcal factor that accounts for the cell death pathways indu...

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Autors principals: Braun, Johann S., Hoffmann, Olaf, Schickhaus, Miriam, Freyer, Dorette, Dagand, Emilie, Bermpohl, Daniela, Mitchell, Tim J., Bechmann, Ingo, Weber, Joerg R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951198/
https://ncbi.nlm.nih.gov/pubmed/17562768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00031-07
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