Cellular and Humoral Immune Responses to Alphavirus Replicon Vaccines Expressing Cytomegalovirus pp65, IE1, and gB Proteins

Development of vaccines against cytomegalovirus (CMV) is an important public health priority. We used a propagation-defective, single-cycle RNA replicon vector system derived from an attenuated strain of an alphavirus, Venezuelan equine encephalitis virus, to produce virus-like replicon particles (V...

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Bibliografiska uppgifter
Huvudupphovsmän: Reap, Elizabeth A., Dryga, Sergey A., Morris, John, Rivers, Bryan, Norberg, Pamela K., Olmsted, Robert A., Chulay, Jeffrey D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Vaccine Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951075/
https://ncbi.nlm.nih.gov/pubmed/17442845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00037-07
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