Enhanced Ex Vivo Stimulation of Mycobacterium tuberculosis-Specific T Cells in Human Immunodeficiency Virus-Infected Persons via Antigen Delivery by the Bordetella pertussis Adenylate Cyclase Vector

The genetically detoxified Bordetella pertussis adenylate cyclase is a promising delivery system for immunodominant tuberculosis antigens in gamma interferon release assays. This system has not been evaluated in human immunodeficiency virus (HIV)-infected persons in high tuberculosis prevalence area...

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Detalhes bibliográficos
Main Authors: Connell, Tom G., Shey, Muki S., Seldon, Ronnett, Rangaka, Molebogeng X., van Cutsem, Gilles, Simsova, Marcela, Marcekova, Zuzana, Sebo, Peter, Curtis, Nigel, Diwakar, Lavanya, Meintjes, Graeme A., Leclerc, Claude, Wilkinson, Robert J., Wilkinson, Katalin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Microbial Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951068/
https://ncbi.nlm.nih.gov/pubmed/17522328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00041-07
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