Identification and In Vivo Functional Analysis by Gene Disruption of ctnA, an Activator Gene Involved in Citrinin Biosynthesis in Monascus purpureus

Citrinin, a secondary fungal metabolite of polyketide origin, is moderately nephrotoxic to vertebrates, including humans. From the red-pigment producer Monascus purpureus, a 21-kbp region flanking pksCT, which encodes citrinin polyketide synthase, was cloned. Four open reading frames (ORFs) (orf1, o...

Full description

Saved in:
Bibliographic Details
Main Authors: Shimizu, Takeo, Kinoshita, Hiroshi, Nihira, Takuya
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Mycology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950990/
https://ncbi.nlm.nih.gov/pubmed/17586673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01979-06
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items