A Discrete Class of Intergenic DNA Dictates Meiotic DNA Break Hotspots in Fission Yeast

Meiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes covalently linked to the DSB ends. Like recombination events, DSBs occur at hotspots in the genome, but the genetic factors responsible for most hotspots have remained elusive....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cromie, Gareth A, Hyppa, Randy W, Cam, Hugh P, Farah, Joseph A, Grewal, Shiv I. S, Smith, Gerald R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2007
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950956/
https://ncbi.nlm.nih.gov/pubmed/17722984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030141
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