Functional conservation of Rel binding sites in drosophilid genomes

Evolutionary constraints on gene regulatory elements are poorly understood: Little is known about how the strength of transcription factor binding correlates with DNA sequence conservation, and whether transcription factor binding sites can evolve rapidly while retaining their function. Here we use...

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Detalles Bibliográficos
Autores principales: Copley, Richard R., Totrov, Maxim, Linnell, Jane, Field, Simon, Ragoussis, Jiannis, Udalova, Irina A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
Materias:
Letter
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950901/
https://ncbi.nlm.nih.gov/pubmed/17785540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6490707
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