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Lethal Contractural Syndrome Type 3 (LCCS3) Is Caused by a Mutation in PIP5K1C, Which Encodes PIPKIγ of the Phophatidylinsitol Pathway

Lethal congenital contractural syndrome (LCCS) is a severe form of arthrogryposis. To date, two autosomal recessive forms of the disease (LCCS and LCCS2) have been described and mapped to chromosomes 9q34 and 12q13, respectively. We now describe a third LCCS phenotype (LCCS3)—similar to LCCS2 yet wi...

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Detalhes bibliográficos
Main Authors: Narkis, Ginat , Ofir, Rivka , Landau, Daniella , Manor, Esther , Volokita, Micha , Hershkowitz, Relly , Elbedour, Khalil , Birk, Ohad S. 
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950840/
https://ncbi.nlm.nih.gov/pubmed/17701898
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