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Genomewide Weighted Hypothesis Testing in Family-Based Association Studies, with an Application to a 100K Scan
For genomewide association (GWA) studies in family-based designs, we propose a novel two-stage strategy that weighs the association P values with the use of independently estimated weights. The association information contained in the family sample is partitioned into two orthogonal components—namel...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society of Human Genetics
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950836/ https://ncbi.nlm.nih.gov/pubmed/17701906 |
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