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Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans

MicroRNAs (miRNAs) are regulatory molecules that share both biosynthetic derivation (cleavage from short hairpin precursor RNAs) and functional roles (downregulation of specific mRNAs through targeted degradation and/or translational inhibition). A distinct family of small RNAs, termed siRNAs, have...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gu, Sam G., Pak, Julia, Barberan-Soler, Sergio, Ali, Mustapha, Fire, Andrew, Zahler, Alan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950768/
https://ncbi.nlm.nih.gov/pubmed/17652138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.581907
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