Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing

After the second transesterification step of pre-mRNA splicing, the Prp22 helicase catalyzes release of spliced mRNA by disrupting contacts in the spliceosome that likely involve Prp8. Mutations at Arg1753 in Prp8, which suppress helicase-defective prp22 mutants, elicit temperature-sensitive growth...

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Detalhes bibliográficos
Main Authors: Aronova, Anna, Bacíková, Dagmar, Crotti, Luciana B., Horowitz, David S., Schwer, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950762/
https://ncbi.nlm.nih.gov/pubmed/17626844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.572807
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