Differential Requirements for MCM Proteins in DNA Replication in Drosophila S2 Cells

BACKGROUND: The MCM2-7 proteins are crucial components of the pre replication complex (preRC) in eukaryotes. Since they are significantly more abundant than other preRC components, we were interested in determining whether the entire cellular content was necessary for DNA replication in vivo. METHOD...

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Hauptverfasser: Crevel, Gilles, Hashimoto, Reina, Vass, Sharron, Sherkow, Jake, Yamaguchi, Masamitsu, Heck, Margarete M.S., Cotterill, Sue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950684/
https://ncbi.nlm.nih.gov/pubmed/17786205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000833
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