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Major Histocompatibility Complex Heterozygosity Reduces Fitness in Experimentally Infected Mice
It is often suggested that heterozygosity at major histocompatibility complex (MHC) loci confers enhanced resistance to infectious diseases (heterozygote advantage, HA, hypothesis), and overdominant selection should contribute to the evolution of these highly polymorphic genes. The evidence for the...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Copyright © 2007 by the Genetics Society of America
2007
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950649/ https://ncbi.nlm.nih.gov/pubmed/17603099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.074815 |
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