SYP-3 Restricts Synaptonemal Complex Assembly to Bridge Paired Chromosome Axes During Meiosis in Caenorhabditis elegans

Synaptonemal complex (SC) formation must be regulated to occur only between aligned pairs of homologous chromosomes, ultimately ensuring proper chromosome segregation in meiosis. Here we identify SYP-3, a coiled-coil protein that is required for assembly of the central region of the SC and for restr...

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Main Authors: Smolikov, Sarit, Eizinger, Andreas, Schild-Prufert, Kristina, Hurlburt, Allison, McDonald, Kent, Engebrecht, JoAnne, Villeneuve, Anne M., Colaiácovo, Mónica P.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2007 by the Genetics Society of America 2007
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950610/
https://ncbi.nlm.nih.gov/pubmed/17565948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.072413
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