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HAL-2 Promotes Homologous Pairing during Caenorhabditis elegans Meiosis by Antagonizing Inhibitory Effects of Synaptonemal Complex Precursors

During meiosis, chromosomes align with their homologous pairing partners and stabilize this alignment through assembly of the synaptonemal complex (SC). Since the SC assembles cooperatively yet is indifferent to homology, pairing and SC assembly must be tightly coordinated. We identify HAL-2 as a ke...

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Detalhes bibliográficos
Main Authors: Zhang, Weibin, Miley, Natasha, Zastrow, Michael S., MacQueen, Amy J., Sato, Aya, Nabeshima, Kentaro, Martinez-Perez, Enrique, Mlynarczyk-Evans, Susanna, Carlton, Peter M., Villeneuve, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415444/
https://ncbi.nlm.nih.gov/pubmed/22912597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002880
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