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Global Changes in Optic Nerve Head Gene Expression after Exposure to Elevated Intraocular Pressure in a Rat Glaucoma Model

PURPOSE: In glaucoma, the optic nerve head (ONH) is the likely site of initial injury and elevated intraocular pressure (IOP) is the best-known risk factor. This study determines global gene expression changes in the pressure-injured ONH. METHODS: Unilateral sustained IOP elevation (glaucoma, n = 46...

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Main Authors: Johnson, Elaine C., Jia, Lijun, Cepurna, William O., Doser, Thomas A., Morrison, John C.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950563/
https://ncbi.nlm.nih.gov/pubmed/17591886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.06-1282
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