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An RNAi-based Approach Identifies New Molecules Required for Glutamatergic and GABAergic Synapse Development
We report the results of a genetic screen to identify molecules important for synapse formation and/or maintenance. siRNAs were used to decrease the expression of candidate genes in neurons, and synapse development was assessed. We surveyed 22 cadherin family members and demonstrated distinct roles...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950560/ https://ncbi.nlm.nih.gov/pubmed/17224404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2006.12.012 |
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