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An RNAi-based Approach Identifies New Molecules Required for Glutamatergic and GABAergic Synapse Development
We report the results of a genetic screen to identify molecules important for synapse formation and/or maintenance. siRNAs were used to decrease the expression of candidate genes in neurons, and synapse development was assessed. We surveyed 22 cadherin family members and demonstrated distinct roles...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950560/ https://ncbi.nlm.nih.gov/pubmed/17224404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2006.12.012 |
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