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Mutation analysis of a recombinant NS replicon shows that influenza virus NS1 protein blocks the splicing and nucleo-cytoplasmic transport of its own viral mRNA
The genome of influenza A virus consists of eight single-stranded RNA molecules of negative polarity. Their replication and transcription take place in the nucleus of infected cells using ribonucleoprotein complexes (RNPs) as templates. Two of the viral transcripts, those generated by RNPs 7 and 8,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950557/ https://ncbi.nlm.nih.gov/pubmed/17488845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm230 |
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