Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline

We applied a computational pipeline based on comparative genomics to bacteria, and identified 22 novel candidate RNA motifs. We predicted six to be riboswitches, which are mRNA elements that regulate gene expression on binding a specific metabolite. In separate studies, we confirmed that two of thes...

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Main Authors: Weinberg, Zasha, Barrick, Jeffrey E., Yao, Zizhen, Roth, Adam, Kim, Jane N., Gore, Jeremy, Wang, Joy Xin, Lee, Elaine R., Block, Kirsten F., Sudarsan, Narasimhan, Neph, Shane, Tompa, Martin, Ruzzo, Walter L., Breaker, Ronald R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2007
Teme:
Genomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950547/
https://ncbi.nlm.nih.gov/pubmed/17621584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm487
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